Cain’s wife was a member of Adam’s family and probably Cain’s sister.

Cain’s Wife (Genesis 4:17)

There are only limited details about Cain’s wife. The only mention of Cain’s wife in the Bible is in Genesis 4:17, where Cain and his wife had a son. They soon named a city after him. The Bible does say that Adam and Eve had more children besides Cain and Abel (Genesis 5:4). No doubt it was one of these daughters that Cain took for a wife.

Intermarriage

The custom of brothers marrying sisters was common as late as the time of Abraham, for in Genesis 20:12 we find that Abraham married his half-sister. In that period of the world men and women had not become diseased, deformed and mentally deficient as they are today. Because of this condition in many families at the present time, close intermarriage between members of the same family is not recommended, seeing as such marriages can exacerbate those deficiencies. 

In Leviticus 18:6-17, Moses prohibited close intermarriages between members of the same family. This was at a time before the link between familial intermarriage and genetic disorders was scientifically documented!

What Does the Bible Say About Cain?

Genesis chapter 4 tells the story of Cain and his wife. The highlights of this chapter include:

• The birth of Cain and Abel
• The sacrifices they bring to the Lord
• Cain killing Abel
• The birth of Cain’s son, Enoch

Please note: there are two Enoch’s mentioned in Genesis. One is a descendant of Cain (Genesis 4:17) and the other a descendant of Seth (Genesis 5:19, 21-24).

The chapter ends with the birth of Seth, Adam and Eve’s third son. “And Adam knew his wife again, and she bore a son and named him Seth, ‘For God has appointed another seed for me instead of Abel, whom Cain killed’” (Genesis 4:25).